¿Cuáles son los métodos de inducción de IPSC?

Las células madre tienen el potencial de diferenciarse en varios tipos de células. Las células madre pluripotentes tienen el potencial de diferenciarse en cualquier tipo de célula. Las células madre pluripotentes inducidas son una línea de células madre pluripotentes que se producen directamente a partir de una célula somática. Las células madre pluripotentes más utilizadas son las células perinatales y las iPSC. Las iPSC tienen un gran potencial en la medicina regenerativa, debido a su potencial para proliferar indefinidamente y dar lugar a cualquier otro tipo de célula en el cuerpo. Las células madre también se pueden utilizar en terapias específicas del paciente para minimizar el riesgo de rechazo del injerto. Las células madre se pueden utilizar en terapias específicas del paciente para minimizar el riesgo de rechazo del injerto. Las iPSC se pueden cultivar con o sin un andamio de soporte.

The discovery in 2006 that human and mouse fibroblasts could be reprogrammed to generate induced pluripotent stem cells (iPSCs) with qualities remarkably similar to embryonic stem cells has created a valuable new source of pluripotent cells for drug discovery, cell therapy, and basic research. Our products have been an integral part of induced pluripotent stem cell research from the initial discovery of iPSCs to current breakthroughs. Our complete portfolio of stem cell research products and services provides optimized tools for each step of the stem cell workflow: from reprogramming somatic cells to iPSC expansion, validation, and differentiation. Reprogramming of somatic cells for iPSC generation can be accomplished with a number of technologies. We offer choices in integration-free reprogramming technologies and services that fit your research and translational needs including our Cell Therapy Systems (CTS) Products, which are designed for clinical and translational research applications. iPSC research requires careful attention to culture conditions. From feeder-based and feeder-free media to optimized passaging reagents and substrates to media for stem cell therapy research, Gibco products enable you to culture with confidence. iPSCs are engineered to analyze disease pathways, better understand gene and protein expression, and study differentiation. Choose from Invitrogen gene editing and transfection technologies to build cell models that can better answer biological questions. iPSC differentiation requires standardized culture methods to ensure reproducible and reliable results. Gibco media, supplements, substrates, growth factors and cytokines provide you with an easy-to-use, flexible set of tools for targeted differentiation of induced pluripotent stem cells. Analyze stem cells and their derivatives using a wide range of cellular and molecular characterization methods, as validation is critical in iPSC research. Whether analyzing proliferation, protein levels, gene expression, or epigenetic profiles, we have the right instruments, products, and services for your research.